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                Canine Keratoacanthoma               

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Keratoacanthoma is an inherited benign nailbed condition and is said to be a less grave type of squamous cell carcinoma. It is a small tumor that affects the skin filled with keratin.  It is often ulcerated on the surface, exposing keratin-like material.  It lies within the skin and grows rapidly over a period of a few weeks giving a dome like appearance.  Many of the Keratoacanthomas appear to grow  and regress like hair follicles themselves and can be considered benign neoplasms.

Diagnosis can be difficult, as it can be very difficult to differentiate this lesion from a well-differentiated squamous cell carcinoma (SCC). The length of history is often the best guide as to the correct diagnosis, as even the pathology can be difficult to interpret. A keratoacanthoma should start to regress spontaneously 6-8 weeks after first appearing. If there is no evidence of this occurring, it should be considered as a squamous cell carcinoma and excised appropriately.

Nailbed keratocanthoma (Subungual Keratoacanthoma)
This is a benign tumor of the nailbed epithelium.  This uncommon tumor has only been described in cats and dogs.  Animals 3-14 years old are affected with no breed or sex preilection noted in cases reported.

The nailbed epithelium of the forelimbs and hindlimbs is the site of the tumor.  The nailbed is often enlarged and may be twisted, ulceration of the adjacent epidermis, loss of nail, and secondary bacterial infection are frequently found.

The tumors are slow growing and are cured by amputation of the affected digit.
Tumors in the Domestic Animals- Donald J Meuten


Nailbed Keratoacanthoma



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