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CANINE VESTIBULAR DISEASE

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Vestibular Syndrome is dizziness caused by a failure of the vestibular system – the organs involved with the sense of balance. The vestibular system consists of part of the inner ear called the semi-circular canals and regions of the brain that process the sense of balance. Usually only one side stops working, so the dog loses its sense of which way up it should be.

The dog appears dizzy or drunk and if it can stand it will tend to walk in circles and fall over to one side. Many dogs are unable to stand and will lie on one side only. The eyes tend to flick from side to side, moving slowly in one direction and flicking quickly back. They will often pant and may vomit. If able to stand, the head will often be tilted to one side.

Vestibular syndrome can be caused by an infection in the middle ear that spreads to affect the inner ear. In these cases, there is often pain in one of the ears and head shaking may have been present for some time previously.

The cause is unknown In most cases of vestibular syndrome. This is known as Idiopathic Vestibular Syndrome. This occurs in older dogs and is often referred to as a “stroke” to help people understand what has happened to their dog, although the cause is not the same as a stroke in humans – there is no blood clot or bleed to cause it. Factors that seem to be related to incidence of this problem include general anaesthetics, heart disease, poor circulation and very hot weather. These are all factors that can affect the blood flow in the brain and all indications are that the cause is a disruption of the blood flow to part of the brain. There are similarities with Meniere’s Disease in humans. It is possible for a blow to the head to cause vestibular syndrome, but this is rare.

Provided that only the vestibular system is affected, the prognosis is usually very good for a full recovery. However, in some cases, other parts of the brain can be affected at the same time. Generally, if the dog is able to recognise its owner and is at least partly aware of what is going on, it will recover eventually.

If an underlying cause is suspected, then treatment must be given for that. A middle ear infection will require antibiotics and anti-inflammatory drugs. No drugs have definitely been proven to help dogs recover from Idiopathic Vestibular Syndrome. An injection of steroid soon after it occurs has been proven to help many brain injuries, so it is possible this will speed recovery. Otherwise drugs that help to improve the blood flow to the brain are often given, such as Vivitonin or Fitergol, particularly if the dog has other evidence of poor circulation.

Treatment is aimed at making the dog more comfortable.  Drugs may be given to prevent vomiting and if the dog is unable to settle, tranquillisers will help. In the early stages it is best for the dog to rest quietly lying down. They may require help taking food and drink until they regain some stability. Once they start to feel better in themselves, particularly after the eyes have stopped flickering, it is useful for them to try and get around. When they first start moving around again, they will be unstable and fall often. To help them through this phase it is best to protect them from falling on hard floors/objects and to loop a towel under the body when they walk to help them. They should not have access to stairs without help. Lifting them off the floor at this stage is often distressing – they learn to use the floor as a reference for their balance. Walking around at this stage will speed their recovery – it is largely a learning process, so practice helps.

Most dogs will make a reasonable recovery within 2 weeks of the problem starting. In many cases, it seems that the damage does not repair, but rather the brain learns to cope with the change in the sense of balance. The dog is often left with a head tilt, usually worse than when the problem first started, but will be able to get around normally. Many people contemplate euthanasia when a vestibular attack occurs. However, if the dog is otherwise in good health and aware of the people around them, the prognosis is good, although it takes a little time. If, however, the dog is already suffering with poor health or seems to have suffered damage to other parts of the brain also, euthansia may be the kindest option.


Vestibular Disease
Canine Vestibular Disease
Vestibular Disease in Cats and Dogs

THE PET HEALTH LIBRARY

By Wendy C. Brooks, DVM, DipABVP
Educational Director, VeterinaryPartner.com 
http://www.VeterinaryPartner.com

Vestibular Disease

WHAT ON EARTH IS THE VESTIBULAR APPARATUS?
In a nutshell, the vestibular apparatus is the neurological equipment responsible for perceiving one's body's orientation relative to the earth (determining if you are upside-down, standing up straight, falling etc.) and informing ones eyes and extremities how they should move accordingly.

The vestibular apparatus allows us to walk, even run, on very uneven ground without falling, helps us know when we need to right ourselves, and allows our eyes to follow moving objects without becoming dizzy.

There are two sets of receptors involved: one to detect rotational acceleration (tumbling or turning) and one to detect linear acceleration and gravity (falling and letting us know which direction is up and which is down). Both receptors are located in the middle ear. Tiny neurological hair cells project into special canals of fluid so that when one's head moves, the fluid moves, and the hair cells wave within the fluid. The hair cells are part of sensory nerve cells which carry the appropriate message to the cerebellum (part of the brain that coordinates locomotion) and to 4 vestibular nuclei in the brain stem.

From these centers, instructions are carried by nerve cells to the legs and neck muscles, and eye muscles so that we may orient ourselves immediately. The information about being upside down (or in some other abnormal orientation) is also sent to the hypothalamus (an area of the brain) so that we can become consciously aware of our position. The information is also sent to the "reticular formation" (another area of the brain - a sort of a volume control on our state of wakefulness. In this way, if we are asleep and start to fall, the vestibular stimulations would wake us up. This is also why rolling an anesthetized animal from side to side is used to hasten anesthetic recovery).

THE SIGNS OF VESTIBULAR DISEASE 
vestibular1
Milou, a dog with vestibular disease, demonstrates a head tilt. At the time of this picture, Milou was not able to walk, but was nearly normal within 4 days.
 
If there is trouble in the vestibular apparatus, then one may not properly perceive one's orientation. To put it more simply, one won't know which way is up, whether or not one is standing up straight or slanted, and one will feel very dizzy.

The following are signs of vestibular disease:

ataxia
(lack of coordination without weakness or involuntary spasms - in other words, stumbling and staggering around)
 
motion sickness
 
nystagmus
(back and forth or rotational eye movements. The movements will be slower in one direction. This is the side where the neurologic lesion is likely to be; however, nystagmus is named according to the direction of the fast component i.e. there may be left nystagmus but the lesion is probably on the right side of the vestibular apparatus.)
 
Circling
 
Head tilt (usually toward the side of the lesion)
 
Falling to one side (usually toward the side of the lesion)
 
Trouble with other nerves controlling the head and face

CAUSES OF VESTIBULAR DISEASE
In order to determine prognosis and choose treatment, one needs to figure out what has happened to the vestibular system. The first step is to determine whether the lesion is central (in the brain) or peripheral ( in the inner ear).

There will be some hints in the clinical presentation. For example, if other cranial nerves are involved and they are on the side opposite from the head tilt, then the lesion is likely to be in the cerebellum (central). If the nystagmus is vertical (the eyes are moving up and down rather than back and forth) or only exists when the animal is placed in certain positions, then the lesion is more likely to be central.

Canine idiopathic vestibular disease (also called "Old dog vestibular disease") and, its feline counterpart, feline idiopathic vestibular disease begin acutely and resolve acutely. Usually improvement is evident in 72 hours and the animal is normal in 7-14 days, possibly with an occasional head tilt persisting. When a case of vestibular disease presents, it may be a good idea to wait a few days to see if improvement occurs before doing diagnostics beyond a routine blood/urine database. These two conditions are idiopathic, meaning we do not know why the occur. We do know that they represent problems in the periphery (nerves of the middle ear rather than in the actual brain.)

IDIOPATHIC VESTIBULAR DISEASE IS THE MOST COMMON FORM OF VESTIBULAR DISEASE IN DOGS AND CATS.

Middle ear infection is a likely possibility for vestibular disease especially if the patient has a history of ear infections. When an otoscope is used to visualize the external ear of an animal with vestibular disease and debris is seen, this would be a good hint that there is infection in the middle ear as well. However, just because debris is not seen in the external ear does not mean that a middle ear infection is unlikely. Special imaging of the middle ear bones may be in order.

The most accessible way to evaluate the middle ear is with a special set of radiographs called a "bulla series" (so named because it focuses on an ear bone called the "tympanic bulla"). If the bulla appears abnormal, the ear may require surgical drainage. The problem is that radiography is often not sensitive enough to pick up damage in the middle ear and a normal set of films does not rule out disease. In these cases, special imaging such as CAT Scan or MRI is better (though rather expensive). These imaging techniques, however, allow imaging of the brain tissue itself (which radiology does not) thus allowing brain abnormalities to be evaluated as well.

If a middle ear infection is present but is not known to be present, a routine cleaning of the external ear can lead to a flare up of vestibular symptoms. This is often unavoidable in long standing ear infections.

Brain tumors can be a cause of vestibular disease if the signs fit with a central lesion. In these cases, special imaging as mentioned above is needed to make the diagnosis. Such tumors may be treatable depending on their location.

Copyright 2001 - 2007 by the Veterinary Information Network, Inc. All rights reserved.
This work was originally published by Veterinary Information Network, Inc. (VIN)
 and is republished with VIN's permission.


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Canine Vestibular Disease

The Peoria Humane Society
http://www.peoriahs.org

One day our 15 year old dog became disoriented, unbalanced and appeared to be confused. He was leaning toward one side, shaking his head, going around in circles, etc. We thought he may have had a stroke and took him to the emergency animal clinic. Instead of stroke it turned out he was suffering from Canine Vestibular Disease—also known as “old dog vestibular syndrome.”

Vestibular means a problem with the connections between inner/middle ear and brain causing ataxia. Dogs with ataxia stand with their limbs braced, they walk with difficulty and have a “drunk” type of motion because they have lost their sense of balance. When the vestibular nerve, which travels from the inner ear to the brain, malfunctions. It disrupts the animal’s sense of balance and orientation.

It is important to find out where the vestibular abnormality is located. The disturbance can be peripheral, meaning it is located outside the brain, or central, located inside the brain. The distinction between the two is subtle and is best diagnosed by a veterinary neurologist. The peripheral disturbance is the most common and least serious.

It has been suggested that there is a correlation between old dog vestibular syndrome and hypothyroidism so blood work should be done to rule out this problem.

The ears should be thoroughly examined because the same symptoms can result from a severe ear mite infection. Also certain types of antibiotics such as streptomycin and gentomicin can cause vestibular syndrome.

This syndrome is not a life threatening condition, nor should it even be called old dog vestibular syndrome because young dogs have also contracted it. However, in most cases old dogs are seen by veterinarians with this condition more often.

Time is a major factor in old dog vestibular syndrome. Recovery time depends on the afflicted dog. Eventually the animal teaches itself to compensate and overcome old dog vestibular. Rest and quiet are required during this recovery time, and it’s important to keep the dog in a well lighted room. If possible, avoid carrying the dog, or, if this is unavoidable, lift the dog slowly and smoothly and hold the pads of it’s feet while airborne. Lifting and moving it through the air disrupts the dog’s sense of orientation. Keeping the dog’s feet firmly on the ground with it’s eyes on the horizon helps regain it’s balance. This condition is sometimes misdiagnosed and dogs who could have recovered have been euthanized because the condition appears so severe. It is important to note that there are no warning signs, which may lead to the conclusion that it is a stroke. Fortunately most dogs will be spared this affliction. However, if your dog does contract this disease, it is comforting to know that it is not fatal and recovery is merely a matter of patience and tender loving care. Please note that a serious inner/middle ear infection—which can occur without the customary smelly ear—has the same severe and frightening symptoms. An infection can usually be cured with antibiotics and the dogs have a complete recovery. Drugs that might be used to treat old dog vestibular syndrome include Cholodin Tabs and Winstrol V. As always, check with your vet.

reprinted with kind permission from Patti Schaffner Peoria Humane Society  phscrc@yahoo.com

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Vestibular Disease in Dogs and Cats

Dr Matthew Homfray
www.whydoesmypet.com

The vestibular system controls balance and prevents an animal from falling over. It does this by holding and constantly adjusting the position of the eyes, head and body in relation to gravity. When there is disease affecting this system, though it is seldom life threatening, the symptoms caused can be particularly distressing for a pet owner. Animals may tilt their head to one side, circle either clockwise or anticlockwise, fall over repeatedly, roll to one side, be generally wobbly and display abnormal pupil movement in their eyes. Here we look at the physiology of the vestibular system in dogs and cats, what can go wrong and how a good veterinarian will diagnose and treat it.

What exactly is the vestibular system?
The vestibular system is a sensory system consisting of a receptor organ within the inner ear, the vestibular nerve itself, and a balance control centre at the back of the brain. The receptor organ in the inner ear detects the position and movement of the head in space, both when the animal is resting or moving. Information on the position of the head is converted into electrical signals, which are transmitted via the vestibular nerve to the brain. The balance control centre in the brain then processed this information, and sends motor signals to the muscles controlling the positions of the eyes and limbs according to the movement of the head.

What is vestibular syndrome?
Vestibular syndrome is a general term describing disease of the vestibular system. The term alone does not provide any information on which part of the vestibular system is affected, and what the cause is.

What are the signs to look out for?
Animals with vestibular disease may display any or all of the following signs:

1. Head tilt
This is rotation of the head so that one ear is lower than the other. It occurs due to loss of antigravity muscle tone on one side of the neck.

2. Circling
Circling often occurs with vestibular disease, but can also occur with forebrain tumors. Generally, tight circles mean vestibular disease while wide circles mean a brain tumor.

3. Nystagmus (wandering pupils)
This means involuntary rhythmic movement of the eyeballs. The pupils tend to drift to one side (the slow phase) and then jerk back to the middle (the fast phase). Usually the slow phase is toward the diseased side.

4. Strabismus (squint)
This means abnormal position of the eyeballs, rather like the condition commonly known as a squint.

5. Ataxia (wobbliness)
This means walking in an uncoordinated fashion, and is seen with a wide range of diseases other than vestibular disease, such as those affecting the brain, spinal cord or peripheral nerves. Animals can adopt a broad based stance, exhibit swaying of the head, and leaning, falling and rolling to one side.

Peripheral vs Central Vestibular Disease
Vestibular disease is categorized as either peripheral or central, according to where in the system the disease originates from. Peripheral vestibular disease is where the disease is located in either the receptor organs in the inner ear or the vestibular nerve. Central vestibular disease is where the disease is located in the balance control centre in the brain (to be precise, either in the brainstem vestibular nuclei or in the cerebellum).

The first task for the veterinarian is to identify whether he/she is dealing with peripheral or central vestibular disease. This is done by looking carefully for all of the symptoms described above, and further characterizing them by direction and nature. It is beyond the remit of this article to go into the exact way of differentiating them clinically, and though it can usually be achieved by a competent vet by examination alone, sometimes further tests are necessary to do so.

Causes of peripheral vestibular syndrome

1. Middle or inner ear disease (infection or tumor)
2. Nasopharyngeal polyps
3. Head trauma
4. Drug toxicity (e.g. gentamycin)
5. Underactive thyroid gland
6. Congenital (present at birth)
7. Idiopathic (cause unidentifiable)

Causes of central vestibular syndrome

1. Brain hemorrhage or infarct
2. Infectious encephalitis (bacterial, viral or fungal)
3. Meningoencephalitis
4. Head trauma
5. Drug toxicity (e.g. metronidazole)
6. Brain cyst
7. Brain tumor (primary or metastatic)
8. Thiamine deficiency
9. Neurodegenerative disease

Making a diagnosis
First, the veterinarian must distinguish between peripheral and central disease based on clinical signs. If there is doubt, diagnostics for both should be done. If the veterinarian suspects central disease, he/she may choose to rule out peripheral disease with various tests first because the tests for central disease are expensive (e.g. MRI or CT scan).

The following procedure is what is most commonly done when looking for causes of peripheral vestibular disease. If drug toxicity has been ruled out (no metronidazole, aminoglycoside antibiotics or topical chlorhexidine recently) then the external ears are examined using an otoscope (illuminated and magnified inspection device with a rigid conical end which is inserted into the ear canal). Ear infections, tumors and polyps may be detected this way. Middle ear disease is suspected if the ear drum appears to be ruptured, bulging, cloudy or red in color. Thyroid levels are usually measured by a blood test at this stage to rule out hypothyroidism.

The next step of the investigation is taking xrays of the skull. Several views are required but the most important one is that which shows the tympanic bullae in the middle ears most clearly. This requires general anesthesia to allow correct positioning.

If the tests at this stage have all come back normal, many cases will be given a presumptive diagnosis of idiopathic vestibular syndrome. This is usually because a) it is by far the most likely diagnosis, and b) further specialized tests are costly. If however further tests are to be carried out, MRI or CT scanning, electromyography and nerve conduction studies are a possibility in some referral centers.
Author: Dr Matthew Homfray
Website: http://www.whydoesmypet.com
Description: A new pet Q&A service connecting pet owners worldwide directly with veterinarians, vet techs, vet nurses, behaviorists, trainers, breeders, groomers, homeopaths and general enthusiasts. Visit us today, you will be impressed by the quality of our experts and the speed with which they respond to your question!
reprinted with kind permission from David Brooks


 
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Vestibular Disease in Animals


chloebutton  talabutton  
 
 The above information is simply informational. It's intent is not to replace the advice of a veterinarian nor to assist you in making a diagnosis of your pet. Please consult with your own veterinarian for confirmation of any diagnosis. Your pets life may depend on it.